Human ALK-1 / ACVRL1 Protein (Fc Tag) 10066-H02H from Sino Biological, Inc. | Biocompare.com

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Human ALK-1 / ACVRL1 Protein (Fc Tag)

Human ALK-1 / ACVRL1 Protein (Fc Tag)

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Sino Biological, Inc. for
Human ALK-1 / ACVRL1 Protein (Fc Tag)

Description

A DNA sequence encoding the N-terminal segment (Met 1-Gln 118) of the extracellular domain of human ALK1 (NP_000011.2) pro-protein was fused with the Fc region of human IgG1 at the C-terminus

Product Specs
ItemHuman ALK-1 / ACVRL1 Protein (Fc Tag)
CompanySino Biological, Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog Number10066-H02H
Conjugate/TagC-human IgG1-Fc
Purity> 97 % as determined by SDS-PAGE
TypeRecombinant protein
Molecular WeightThe mature recombinant human ALK1/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer comprises 335 amino acids and has a predicted molecular mass of 37.4 kDa. As a result of glycosylation, the recombinant monomer migrates as an approximately 45-50 kDa protein in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NameACVRL1
Source/Expression SystemHEK293 Cells
NCBI Full Gene Nameactivin A receptor like type 1
NCBI Gene AliasesACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
Activity1. Measured by its ability to bind Human ENG-Fc (Cat:10149-H02H) in functional Elisa. 2. Measured by its ability to inhibit BMP9 induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells. The ED50 for this effect is typically 1-6 ng/mL in the presence of 2 ng/mL of recombinant human BMP9
FormatLyophilized from sterile PBS, pH 7.4
Quantity100µg

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Sino Biological, Inc.

Sino Biological, Inc.

1400 Liberty Ridge Drive

Suite 101

Wayne, PA 19087

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: http://www.sinobiological.com/

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